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Adaptive Logit Fusion for Mitigating Class Imbalance in Multi-Category Sperm Morphology Assessment

dc.contributor.authorOzge, Emin Can
dc.contributor.authorIlhan, Hamza Osman
dc.contributor.authorSerbes, Gorkem
dc.contributor.authorUzun, Hakki
dc.contributor.authorKaraca, Ali Can
dc.contributor.authorYigit, Merve Huner
dc.date.accessioned2026-06-27T15:32:25Z
dc.date.issued2026
dc.description.abstractSperm morphology is one of the most critical indicators of male fertility. This paper presents a deep learning-based approach to classify sperm cells into 18 morphological classes, including one normal and 17 abnormal types. Two state-of-the-art convolutional neural networks, EfficientNetV2-S and ResNet50V2, are employed and fine-tuned using a class-weighted loss function together with extensive data augmentation to improve generalization under class imbalance. Automatic mixed precision training is adopted to reduce memory consumption and accelerate the training process. An ensemble strategy is subsequently constructed by linearly fusing the logits of both architectures, where the fusion weight is optimized to maximize recall, precision, and overall F1-score. Experimental results show that the proposed ensemble achieves an overall accuracy of 70.94%, consistently outperforming the individual models. Sperm cells with pronounced structural abnormalities, such as PinHead and DoubleTail, are classified with high accuracy, whereas less visually distinctive defects result in comparatively lower performance. These findings demonstrate the potential of CNN-based ensemble models to provide consistent and reliable automated sperm morphology classification.en
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TBIdot
dc.description.sponsorshipTAK) [122E164]
dc.description.sponsorshipRecep Tayyip Erdogbreve
dc.description.sponsorshipan University Development Foundation [02026001015037]
dc.description.urihttps://doi.org/10.3390/life16030438
dc.identifier.doi10.3390/life16030438
dc.identifier.eissn2075-1729
dc.identifier.issue3
dc.identifier.pubmed41900957
dc.identifier.urihttps://hdl.handle.net/20.500.14981/71707
dc.identifier.volume16
dc.identifier.wos001726395500001
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofLIFE-BASEL
dc.rightsopenAccess
dc.subjectsperm morphology
dc.subjectadaptive logit fusion
dc.subjectensemble learning
dc.subjectEfficientNetV2-S
dc.subjectinfertility
dc.subjectLife Sciences & Biomedicine - Other Topics
dc.subjectMicrobiology
dc.titleAdaptive Logit Fusion for Mitigating Class Imbalance in Multi-Category Sperm Morphology Assessment
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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