Synthesis of new N-norbornylimide substituted amide derivatives, their reductive Heck and domino Heck reactions

Abstract

Palladium-catalyzed, regioselective hydroarylation reactions of N-norbornenylimide substituted amides were studied to synthesize pentanamide derivatives containing exo-aryl-substituted norbornyl imide groups in excellent yields. All newly synthesized derivatives have been characterized by FTIR, H-1, C-13 NMR, GC/MS and TOF/Qtof analyses.