Transformations of 4-N-arylamino-4-(8-quinolinyl)-1-butenes and 3-aryl-2-(8-quinolinyl)4-thiazolidinones

Abstract

The chemistry of 4-N-arylamino-4-(8-quinolinyl)-1-butenes 1-5 and 3-aryl-2-(8-quinolinyl)-4-thiazolidinones 15 has been studied. N-Furoylation, N-allylation, mediated-acid intramolecular cyclisation. amino-Claisen transposition and aldol reactions were used to prepare new C-8 substituted quinolines with biological potential.