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Indirect determination of some analgesic-inflammatory drugs by AAS

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dc.contributor.authorAlpdogan, G
dc.contributor.authorSungur, S
dc.date.accessioned2026-06-27T12:56:06Z
dc.date.issued1999
dc.description.abstractAn Indirect AAS method has been developed for the determination of analgesic-inflammatory drugs, mefenamic acid, flufenamic acid and diclofenac sodium. The method depends on the complexation with copper (II) ammine sulphate. The complex was extracted into chloroform and the concentrations of substances were determined indirectly by AAS measurement of copper, after reextraction into 0.3 N nitric acid solution. The developed method was applied to the assay of the drug substances in commercial tablet formulations. The results were statistically compared with those obtained by HPLC method by t- and F-tests at 95% confidence level. Calculated t and F values were both lower than the table values.en
dc.description.urihttps://doi.org/10.1080/00032719908543007
dc.identifier.doi10.1080/00032719908543007
dc.identifier.endpage2808
dc.identifier.issn0003-2719
dc.identifier.issue14
dc.identifier.startpage2799
dc.identifier.urihttps://hdl.handle.net/20.500.14981/47832
dc.identifier.volume32
dc.identifier.wos000083313600008
dc.language.isoeng
dc.publisherMARCEL DEKKER INC
dc.relation.ispartofANALYTICAL LETTERS
dc.subjectmefenamic acid
dc.subjectflufenamic acid
dc.subjectdiclofenac sodium
dc.subjectatomic absorption spectrophotometry
dc.subjectNONSTEROIDAL ANTIINFLAMMATORY DRUGS
dc.subjectSPECTROPHOTOMETRIC DETERMINATION
dc.subjectPHARMACEUTICAL PREPARATIONS
dc.subjectACID
dc.subjectTLC
dc.subjectChemistry
dc.titleIndirect determination of some analgesic-inflammatory drugs by AAS
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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