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Investigation of singlet oxygen efficiency of di-axially substituted silicon phthalocyanine with sono-photochemical and photochemical studies

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dc.contributor.authorAtmaca, Goknur Yasa
dc.date.accessioned2026-06-27T14:31:07Z
dc.date.issued2021
dc.description.abstractSono-photodynamic therapy (SPDT) is a favorable new modality for the treatment of the tumor cells. Although SPDT improves the therapeutic outcomes in cell applications, unlike PDT, SPDT studies are insufficient. In this study, to contribute to the development of SPDT, a promising sensitizer was synthesized, characterized, and analyzed photophysico-chemical properties. Afterwards, the singlet oxygen quantum yield of the sensitizer was calculated by both photochemical and sono-photochemical studies. When the methods are compared, the sono-photochemical studies (Phi(Delta) = 0.71 in DMSO, 0.65 in DMF) were found more effective than the photochemical studies (Phi(Delta) = 0.47 DMSO, 0.41 in DMF) in terms of producing singlet oxygen. This report will pave the way for the synthesis of new sensitizers to be used in SPDT. (C) 2020 Elsevier Ltd. All rights reserved.en
dc.description.urihttps://doi.org/10.1016/j.poly.2020.114894
dc.identifier.doi10.1016/j.poly.2020.114894
dc.identifier.eissn1873-3719
dc.identifier.issn0277-5387
dc.identifier.urihttps://hdl.handle.net/20.500.14981/61549
dc.identifier.volume193
dc.identifier.wos000598081300012
dc.language.isoeng
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD
dc.relation.ispartofPOLYHEDRON
dc.subjectSonochemical properties
dc.subjectPhotochemical properties
dc.subjectPhthalocyanine
dc.subjectSinglet oxygen
dc.subjectChemistry
dc.subjectCrystallography
dc.titleInvestigation of singlet oxygen efficiency of di-axially substituted silicon phthalocyanine with sono-photochemical and photochemical studies
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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