Synthesis of α-aminonitriles catalyzed by montmorillonite K10 in the presence of dicationic phosphonium salt in water under ultrasonic effect

Abstract

The synthesis of alpha-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S) alpha-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.