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Antiviral activity of Sanicula europaea L. extracts on multiplication of human parainfluenza virus type 2

dc.contributor.authorKaragöz, A
dc.contributor.authorArda, N
dc.contributor.authorGören, N
dc.contributor.authorNagata, K
dc.contributor.authorKuru, A
dc.date.accessioned2026-06-27T12:59:43Z
dc.date.issued1999
dc.description.abstractThe antiviral activity of Sanicula europaea L. extracts against human parainfluenza virus type 2 (HPIV-2) was examined, The extract prepared from the leaves of the plant and a fraction separated from the crude extract with gel filtration chromatography were found to inhibit HPIV-2 replication without any toxic effect on Vero cells. The acidic fraction obtained from the crude extract of S. europaea leaves was found to be the most active fraction with plaque inhibition assay at non-cytotoxic concentrations. Unfortunately, antiviral activity was not detected in the molecules purified from the crude ethanol extract of Sanicula leaves. Copyright (C) 1999 John Wiley & Sons, Ltd,en
dc.description.urihttps://doi.org/10.1002/(sici)1099-1573(199908/09)13:5<436::aid-ptr459>3.0.co;2-q
dc.identifier.doi10.1002/(sici)1099-1573(199908/09)13:5<436::aid-ptr459>3.0.co;2-q
dc.identifier.endpage438
dc.identifier.issn0951-418X
dc.identifier.issue5
dc.identifier.pubmed10441789
dc.identifier.startpage436
dc.identifier.urihttps://hdl.handle.net/20.500.14981/48719
dc.identifier.volume13
dc.identifier.wos000082182900017
dc.language.isoeng
dc.publisherJOHN WILEY & SONS LTD
dc.relation.ispartofPHYTOTHERAPY RESEARCH
dc.subjectSanicula europaea L.
dc.subjectApiaceae (Umbelliferaea)
dc.subjectantiviral activity
dc.subjectparainfluenza
dc.subjectPharmacology & Pharmacy
dc.titleAntiviral activity of Sanicula europaea L. extracts on multiplication of human parainfluenza virus type 2
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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