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An investigation into domino-Heck reactions of N-acylamino-substituted tricyclic imides:: Synthesis of new prospective pharmaceuticals

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dc.contributor.authorBagdatli, Emine
dc.contributor.authorOcal, Nueket
dc.contributor.authorKaufmann, Dieter E.
dc.date.accessioned2026-06-27T13:04:56Z
dc.date.issued2007
dc.description.abstractHeck and domino-Heck reactions of unsaturated N-acylamino-substituted tricyclic imides with aryl(heteroaryl) iodides and phenyl- or (trimethylsilyl)acetylene were either carried out in the presence of formate or phenyl- and (trimethylsilyl) acetylene, respectively. The C-C coupling reactions appeared to be completely diastereoselective, giving the corresponding N-acylamino-5-exo-aryl (heteroaryl)- (5a-c, 6a,b),N-(benzoylamino)-5-exo-phenyl-6-exo-[(trimethylsilyl)ethynyl]- (5d), or 5-exo-(4-chlorophenyl)-N-(2,2-dimethylpropanoylamino)-6-exo-(phenylethynyl)bicyclo[2.2.1]heptane-2-endo,3-endo-dicar- boximide (6c) (Schenzes 3 and 4).en
dc.description.urihttps://doi.org/10.1002/hlca.200790244
dc.identifier.doi10.1002/hlca.200790244
dc.identifier.eissn1522-2675
dc.identifier.endpage2385
dc.identifier.issn0018-019X
dc.identifier.issue12
dc.identifier.startpage2380
dc.identifier.urihttps://hdl.handle.net/20.500.14981/49450
dc.identifier.volume90
dc.identifier.wos000252543700010
dc.language.isoeng
dc.publisherWILEY-V C H VERLAG GMBH
dc.relation.ispartofHELVETICA CHIMICA ACTA
dc.subjectPALLADIUM-CATALYZED REACTIONS
dc.subjectCYCLIC IMIDES
dc.subjectEPIBATIDINE
dc.subjectCHEMISTRY
dc.subjectLIGAND
dc.titleAn investigation into domino-Heck reactions of N-acylamino-substituted tricyclic imides:: Synthesis of new prospective pharmaceuticals
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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