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SIMULTANEOUS DETERMINATION OF ACETAMINOPHEN AND CAFFEINE IN TABLET PREPARATIONS BY PARTIAL LEAST-SQUARES MULTIVARIATE SPECTROPHOTOMETRIC CALIBRATION

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dc.contributor.authorBOZDOGAN, A
dc.contributor.authorACAR, AM
dc.contributor.authorKUNT, GK
dc.date.accessioned2026-06-27T12:57:04Z
dc.date.issued1992
dc.description.abstractThe use of partial least-squares spectrophotometric calibration for the simultaneous determination of analgesic tablets in a multicomponent formulation is presented. This method is applied to the determination of acetaminophen and caffeine in tablet preparations. The results show that these components in a molar ratio of about 21:1 in tablets have been determined simultaneously with high precision.en
dc.description.urihttps://doi.org/10.1016/0039-9140(92)80281-h
dc.identifier.doi10.1016/0039-9140(92)80281-h
dc.identifier.endpage979
dc.identifier.issn0039-9140
dc.identifier.issue8
dc.identifier.pubmed18965481
dc.identifier.startpage977
dc.identifier.urihttps://hdl.handle.net/20.500.14981/48071
dc.identifier.volume39
dc.identifier.wosA1992JD01500016
dc.language.isoeng
dc.publisherELSEVIER SCIENCE BV
dc.relation.ispartofTALANTA
dc.subjectMULTICOMPONENT
dc.subjectChemistry
dc.titleSIMULTANEOUS DETERMINATION OF ACETAMINOPHEN AND CAFFEINE IN TABLET PREPARATIONS BY PARTIAL LEAST-SQUARES MULTIVARIATE SPECTROPHOTOMETRIC CALIBRATION
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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