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Cytotoxic effects of bulk fill composite resins on human dental pulp stem cells

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dc.contributor.authorSisman, Reyhan
dc.contributor.authorAksoy, Ayca
dc.contributor.authorYalcin, Muhammet
dc.contributor.authorKaraoz, Erdal
dc.date.accessioned2026-06-27T13:55:30Z
dc.date.issued2016
dc.description.abstractFive bulk fill composite resins, including SDR, Tetric EvoCeram Bulk Fill (TEC), X-trafil (XTF), Sonic Fill (SF), Filtek Bulk Fill (FBF), were used in this study. Human dental pulp stem cells were cultured in 12-well culture dishes (3 x 104 cells per cm(2)) and stored in an incubator at 37 degrees C and 5% CO2 for 1 day. On days 1, 7, 14, and 21 of co-culture, viable cells were measured using a WST-1 assay. Lower cell viability was observed with XTF and SDR bulk fill composite resins compared to the control group during the WST-1 assay. Although bulk fill composite resins provide advantages in practical applications, they are limited by their cytotoxic properties.en
dc.description.urihttps://doi.org/10.2334/josnusd.15-0603
dc.identifier.doi10.2334/josnusd.15-0603
dc.identifier.eissn1880-4926
dc.identifier.endpage305
dc.identifier.issn1343-4934
dc.identifier.issue3
dc.identifier.pubmed27665967
dc.identifier.startpage299
dc.identifier.urihttps://hdl.handle.net/20.500.14981/55772
dc.identifier.volume58
dc.identifier.wos000383414100001
dc.language.isoeng
dc.publisherNIHON UNIV, SCHOOL DENTISTRY
dc.relation.ispartofJOURNAL OF ORAL SCIENCE
dc.rightsopenAccess
dc.subjectbulk fill composite resin
dc.subjecthuman dental pulp stem cell
dc.subjectcytotoxicity
dc.subjectIN-VITRO CYTOTOXICITY
dc.subjectGLASS-IONOMER CEMENTS
dc.subjectLEACHABLE COMPONENTS
dc.subjectCONVERSION
dc.subjectVIABILITY
dc.subjectMONOMER
dc.subjectELUTION
dc.subjectHEMA
dc.subjectEXPRESSION
dc.subjectCOMPOMERS
dc.subjectDentistry, Oral Surgery & Medicine
dc.subjectMaterials Science
dc.titleCytotoxic effects of bulk fill composite resins on human dental pulp stem cells
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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