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Paper-based analytical devices for virus detection: Recent strategies for current and future pandemics

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dc.contributor.authorOzer, Tugba
dc.contributor.authorHenry, Charles S.
dc.date.accessioned2026-06-27T14:38:44Z
dc.date.issued2021
dc.description.abstractThe importance of user-friendly, inexpensive, sensitive, and selective detection of viruses has been highlighted again due to the recent Coronavirus disease 2019 (COVID-19) pandemic. Among the analytical tools, paper-based devices (PADs) have become a leading alternative for point-of-care (POC) testing. In this review, we discuss the recent development strategies and applications in nucleic acid based, antibody/antigen-based and other affinity-based PADs using optical and electrochemical detection methods for sensing viruses. In addition, advantages and drawbacks of presented PADs are identified. Current state and insights towards future perspectives are presented regarding developing POC diagnosis platform for COVID-19. This review considers state-of-the-art technologies for further development and improvement in PADs performance for virus detection. (c) 2021 Elsevier B.V. All rights reserved.en
dc.description.sponsorshipresearch program of The Scientific and Technological Research Council of Turkey
dc.description.sponsorshipNational Science and Technology Development Agency of Thailand [120N615]
dc.description.sponsorshipUS National Science Foundation [CHEM1710222]
dc.description.sponsorshipUS National Institutes of Health [R21EB030349]
dc.description.sponsorshipNational Institute of Biomedical Imaging and Bioengineering [R21EB030349] Funding Source: NIH RePORTER
dc.description.urihttps://doi.org/10.1016/j.trac.2021.116424
dc.identifier.doi10.1016/j.trac.2021.116424
dc.identifier.eissn1879-3142
dc.identifier.issn0165-9936
dc.identifier.pubmed34462612
dc.identifier.urihttps://hdl.handle.net/20.500.14981/63043
dc.identifier.volume144
dc.identifier.wos000712330500002
dc.language.isoeng
dc.publisherELSEVIER SCI LTD
dc.relation.ispartofTRAC-TRENDS IN ANALYTICAL CHEMISTRY
dc.rightsopenAccess
dc.subjectPaper-based
dc.subjectVirus detection
dc.subjectCOVID-19
dc.subjectSARS-CoV-2
dc.subjectPoint of care
dc.subjectInfectious diseases
dc.subjectOptical
dc.subjectElectrochemical
dc.subjectNanomaterials
dc.subjectLATERAL-FLOW ASSAY
dc.subjectPOINT-OF-CARE
dc.subjectELECTROCHEMICAL DNA-BIOSENSORS
dc.subjectNUCLEIC-ACID AMPLIFICATION
dc.subjectMICROFLUIDIC DEVICES
dc.subjectHEPATITIS-B
dc.subjectARTIFICIAL-INTELLIGENCE
dc.subjectSENSITIVE DETECTION
dc.subjectRAPID DETECTION
dc.subjectZIKA VIRUS
dc.subjectChemistry
dc.titlePaper-based analytical devices for virus detection: Recent strategies for current and future pandemics
dc.typeReview
dspace.entity.typePublication
local.import.sourceWOS

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