Yayın:
Synthesis of New Di- and Triamides as Potential Organocatalysts for Asymmetric Aldol Reaction in Water

Basit öğe sayfası
dc.contributor.authorKeskin, Elif
dc.contributor.authorYolacan, Cigdem
dc.contributor.authorAydogan, Feray
dc.date.accessioned2026-06-27T14:31:41Z
dc.date.issued2020
dc.description.abstractNew di- or triamide organocatalysts derived from (L)-proline were synthesized and successfully used in the direct asymmetric aldol reaction of aliphatic ketones and aromatic aldehydes in water at 0 degrees C in the presence of benzoic acid as co-catalyst. (S)-methyl-24(S)-3-hydroxy-2-((S)-3-pyrrolidine-2-carb oxamido)prop an amido) -3-phenylprop ano ate (7c) as organocatalyst showed best results under these reaction conditions, and good diastereoselectivities (up to 99%), enantioselectivities (up to 98%) and yields (up to 91%) were observed.en
dc.description.sponsorshipYildiz Technical University Scientific Research Foundation [2015-01-02-YL09]
dc.description.urihttps://doi.org/10.17344/acsi.2018.4748
dc.identifier.doi10.17344/acsi.2018.4748
dc.identifier.eissn1580-3155
dc.identifier.endpage1023
dc.identifier.issn1318-0207
dc.identifier.issue4
dc.identifier.pubmed33533456
dc.identifier.startpage1014
dc.identifier.urihttps://hdl.handle.net/20.500.14981/61663
dc.identifier.volume67
dc.identifier.wos000599419000002
dc.language.isoeng
dc.publisherSLOVENSKO KEMIJSKO DRUSTVO
dc.relation.ispartofACTA CHIMICA SLOVENICA
dc.rightsopenAccess
dc.subjectAldol reaction
dc.subjectorganocatalysis
dc.subjectasymmetric synthesis
dc.subjectprolinamide
dc.subjectL-PROLINE
dc.subjectAMINO ACID
dc.subjectCATALYST
dc.subjectEFFICIENT
dc.subjectPEPTIDES
dc.subjectDERIVATIVES
dc.subjectDIPEPTIDES
dc.subjectChemistry
dc.titleSynthesis of New Di- and Triamides as Potential Organocatalysts for Asymmetric Aldol Reaction in Water
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

Dosyalar

Koleksiyonlar

Yayınlar