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Controlled release of donepezil hydrochloride from the ternary sodium alginate based hydrogels

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dc.contributor.authorAkyol, E.
dc.contributor.authorSenol, S.
dc.contributor.authorDogan, O.
dc.date.accessioned2026-06-27T14:05:34Z
dc.date.issued2017
dc.description.abstractIn the presented work, synthesis of the ternary sodium alginate based hydrogels as drug delivery systems having different properties and drug release experiments were performed. For this purpose, gelatine, alpha-cellulose, clinoptilolite, modified clinoptilolite and 4-acryloyl morpholine (4 AcM) were combined with sodium alginate (NaAlg). Hydrogels were characterized by Fourier transform infrared spectroscopy (FT-IR) and digital microscope. In vitro drug release studies have been performed for Donepezil hydrochloride loaded hydrogels at pH 1.2, 6.8 and 7.4. The results showed that these hydrogels can be used for drug delivery systems.en
dc.identifier.endpage63
dc.identifier.issn0324-1130
dc.identifier.startpage57
dc.identifier.urihttps://hdl.handle.net/20.500.14981/56897
dc.identifier.volume49
dc.identifier.wos000413538600009
dc.language.isoeng
dc.publisherBULGARIAN ACAD SCIENCE
dc.relation.conference3rd International Conference on New Trends in Chemistry
dc.relation.ispartofBULGARIAN CHEMICAL COMMUNICATIONS
dc.subjectThe ternary sodium alginate based hydrogels
dc.subjectdrug release
dc.subjectDonepezil hydrochloride
dc.subjectDRUG-DELIVERY
dc.subjectIN-VITRO
dc.subjectCROSS-LINKING
dc.subjectSYSTEMS
dc.subjectChemistry
dc.titleControlled release of donepezil hydrochloride from the ternary sodium alginate based hydrogels
dc.typeArticle; Proceedings Paper
dspace.entity.typePublication
local.import.sourceWOS

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