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Synthesis of microwave-assisted poly(methyl vinyl ether-co-maleic anhydride)-bovine serum albumin bioconjugates

dc.contributor.authorKarahan, Mesut
dc.contributor.authorTuglu, Sevecen
dc.contributor.authorMustafaeva, Zeynep
dc.date.accessioned2026-06-27T13:17:36Z
dc.date.issued2012
dc.description.abstractThe water-soluble poly(methyl vinyl ether-co-maleic anhydride) copolymer-bovine serum albumin bioconjugates were synthesized in the presence of 1-ethyl-3-(3-dimetilaminopropyl) carbodiimide hydrochloride as cross-linking agents via microwave-assisted and conventional methods and characterized by size-exclusion chromatography and high-performance liquid chromatography. According to size-exclusion chromatography and high-performance liquid chromatography results, the bioconjugates synthesized in the microwave-assisted method are more stable and efficient than the conventional method. The reaction time is shortened from 17 hours to 15 minutes by means of the microwave-assisted method.en
dc.description.sponsorshipT.R. Prime Ministry State Planning Organization [25-DPT-07 - 04-01]
dc.description.urihttps://doi.org/10.3109/10731199.2012.678942
dc.identifier.doi10.3109/10731199.2012.678942
dc.identifier.eissn1532-4184
dc.identifier.endpage368
dc.identifier.issn1073-1199
dc.identifier.issue6
dc.identifier.pubmed22540947
dc.identifier.startpage363
dc.identifier.urihttps://hdl.handle.net/20.500.14981/51561
dc.identifier.volume40
dc.identifier.wos000311817900001
dc.language.isoeng
dc.publisherINFORMA HEALTHCARE
dc.relation.ispartofARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY
dc.subjectPolyelectrolyte
dc.subjectprotein
dc.subjectwater soluble bioconjugate
dc.subjectmicrowave-assisted
dc.subjectPERFORMANCE LIQUID-CHROMATOGRAPHY
dc.subjectWATER-SOLUBLE COMPLEXES
dc.subjectPOTENTIOMETRIC TITRATION
dc.subjectLIGHT-SCATTERING
dc.subjectACID
dc.subjectCOPOLYMERS
dc.subjectPOLYMERS
dc.subjectBiotechnology & Applied Microbiology
dc.subjectEngineering
dc.subjectMaterials Science
dc.titleSynthesis of microwave-assisted poly(methyl vinyl ether-co-maleic anhydride)-bovine serum albumin bioconjugates
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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