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Photoinduced in situ formation of clickable PEG hydrogels and their antibody conjugation

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dc.contributor.authorKahveci, Muhammet U.
dc.contributor.authorCiftci, Mustafa
dc.contributor.authorEvran, Serap
dc.contributor.authorTimur, Suna
dc.contributor.authorYagci, Yusuf
dc.date.accessioned2026-06-27T13:31:55Z
dc.date.issued2015
dc.description.abstractA simple approach for the preparation of a clickable poly(ethylene glycol)-based hydrogel as a polymeric support for protein immobilization via photoinitiated free radical polymerization of poly(ethylene glycol) diacrylate and propargyl acrylate is established. Bioconjugation to the obtained gels was achieved by azide-alkyne click reaction with azido-functionalized anti-immunoglobulin G (anti-IgG) and anti-His tag antibodies. Evaluation of the affinities of the PEG hydrogels to the corresponding substrates (IgG and His-tagged YFP, respectively) indicates their specific binding capability.en
dc.description.sponsorshipIstanbul Technical University Research Fund
dc.description.sponsorshipTUBITAK (The Scientific and Technical Research Council of Turkey) [113Z234]
dc.description.sponsorshipTUBITAK
dc.description.urihttps://doi.org/10.1080/15685551.2014.971392
dc.identifier.doi10.1080/15685551.2014.971392
dc.identifier.eissn1568-5551
dc.identifier.endpage136
dc.identifier.issn1385-772X
dc.identifier.issue2
dc.identifier.startpage129
dc.identifier.urihttps://hdl.handle.net/20.500.14981/53618
dc.identifier.volume18
dc.identifier.wos000345688800004
dc.language.isoeng
dc.publisherTAYLOR & FRANCIS LTD
dc.relation.ispartofDESIGNED MONOMERS AND POLYMERS
dc.subjectprotein adsorption
dc.subjectclick chemistry
dc.subjectbioconjugation
dc.subjectphotopolymerization
dc.subjecthydrogels
dc.subjectAMPHIPHILIC GRAFT-COPOLYMERS
dc.subjectMIKTOARM STAR COPOLYMERS
dc.subjectTHIOL-ENE
dc.subjectRADICAL POLYMERIZATION
dc.subjectCROSS-LINKING
dc.subjectCHEMISTRY
dc.subjectPROTEIN
dc.subjectFUNCTIONALIZATION
dc.subjectMETHACRYLATE
dc.subjectCOMBINATION
dc.subjectPolymer Science
dc.titlePhotoinduced in situ formation of clickable PEG hydrogels and their antibody conjugation
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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