SYNTHESIS AND CHARACTERIZATION OF ANTIGENIC PEPTIDE OF SHEEP POX DISEASE

Abstract

The aims of this study are to synthesize the Sheep-Pox Diseases' 92-118 antigenic peptide sequence epitope belonging to P32 major protein by microwave supported solid phase peptide synthesis method, characterize the synthesized peptide and bind it covalently to polyacrylic acid polymer (PAA). This polymer showing adjuvant properties, peptide-polymer conjugates synthesize with constant peptide ratios and various polymer ratios and characterize the peptide-polymer conjugate in order to prepare a vaccine prototype for the aforementioned disease is another purpose of the study.