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Synthesis of novel cyano quinoline derivatives

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dc.contributor.authorOkten, Salih
dc.contributor.authorCakmak, Osman
dc.date.accessioned2026-06-27T13:43:00Z
dc.date.issued2015
dc.description.abstract6,8-Dibromo-1,2,3,4-tetrahydroquinoline (2) and 3,6,8-tribromoquinoline (3) were converted into the corresponding cyano derivatives via copper assisted nucleophilic substitution reactions. While bromination of 6-bromo-8-cyanotetrahydroquinoline (11) gave 3,6-dibromo-8-cyanoquinoline (8), the reaction of dicyano-1,2,3,4-tetrahydroquinoline (12) resulted in the formation of an unexpected dimer (15). (C) 2015 Elsevier Ltd. All rights reserved.en
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [112T394]
dc.description.urihttps://doi.org/10.1016/j.tetlet.2015.07.092
dc.identifier.doi10.1016/j.tetlet.2015.07.092
dc.identifier.endpage5340
dc.identifier.issn0040-4039
dc.identifier.issue39
dc.identifier.startpage5337
dc.identifier.urihttps://hdl.handle.net/20.500.14981/54409
dc.identifier.volume56
dc.identifier.wos000361252200006
dc.language.isoeng
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD
dc.relation.ispartofTETRAHEDRON LETTERS
dc.subjectQuinoline
dc.subjectBromo quinoline
dc.subjectCyano quinoline
dc.subjectBromination
dc.subjectMEK MAPKK INHIBITORS
dc.subjectFRIEDLANDER SYNTHESIS
dc.subjectEFFICIENT
dc.subjectChemistry
dc.titleSynthesis of novel cyano quinoline derivatives
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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