Yayın: Domino-Heck Type Reactions of N-Benzoyl-2-Azabicyclo [2.2.1]Hept-5-ene-3-one
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DOI
10.1007/978-1-4020-6955-0_37
Özet
The coupling of 2-azabicyclo[2.2.1]hept-5-en-3-one and trimethylsilylacetylene or phenylacetylene under Domino Heck conditions gives compounds 2a-c and 4a-c in moderate yields and cyclopentene derivatives, 3a-c in low yields. The procedure can be of use for the synthesis of alkynyl bicyclic lactams.
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INNOVATIONS IN CHEMICAL BIOLOGY
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978-1-4020-6954-3