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Hydroarylation of bicyclic, unsaturated dicarboximides: access to aryl-substituted, bridged perhydroisoindoles

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dc.contributor.authorGoksu, Goekce
dc.contributor.authorGul, Melek
dc.contributor.authorOcal, Nueket
dc.contributor.authorKaufmann, Dieter E.
dc.date.accessioned2026-06-27T13:08:45Z
dc.date.issued2008
dc.description.abstractThe C-C coupling of the two bicyclic, unsaturated dicarboximides 6 and 8 with aryl and hetaryl halides gave under reductive Heck conditions the 5-substituted N-phenylbicyclo[2.2.1]heptane-2,3-dicarboxim ides 7 and 9. Reduction of these imides opens a new access to the bridged perhydroisoindole derivatives 12 and 14 with prospective biological activity. (c) 2008 Elsevier Ltd. All rights reserved.en
dc.description.urihttps://doi.org/10.1016/j.tetlet.2008.02.171
dc.identifier.doi10.1016/j.tetlet.2008.02.171
dc.identifier.eissn1873-3581
dc.identifier.endpage2688
dc.identifier.issn0040-4039
dc.identifier.issue17
dc.identifier.startpage2685
dc.identifier.urihttps://hdl.handle.net/20.500.14981/50352
dc.identifier.volume49
dc.identifier.wos000255270500003
dc.language.isoeng
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD
dc.relation.ispartofTETRAHEDRON LETTERS
dc.subjectpalladium
dc.subjecthomogenous catalysis
dc.subjectC-C coupling
dc.subjectreduction
dc.subjectamine
dc.subjectaromatics
dc.subjectPALLADIUM-CATALYZED REACTIONS
dc.subjectDOMINO-HECK REACTIONS
dc.subjectCYCLIC IMIDES
dc.subjectEPIBATIDINE
dc.subjectAMINES
dc.subjectChemistry
dc.titleHydroarylation of bicyclic, unsaturated dicarboximides: access to aryl-substituted, bridged perhydroisoindoles
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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