Yayın: SYNTHESIS OF NEW TANDOSPIRONE ANALOGUES CARRYING 1-(3-(TRIFLUOROMETHYL)PHENYL)PIPERAZINE
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Dergi Başlığı
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Yayıncı
TAYLOR & FRANCIS INC
DOI
10.1080/00397911.2013.865236
Türü
Özet
New tandospirone analogues containing a 1-[3-(trifluoromethyl) phenyl] piperazine (TFMPP) moiety have been synthesized by hydroarylation reactions with Pd(OAc)(2). The perhydroisoindole derivatives were obtained by the reaction of reduced starting material with aryl-(heteroaryl) iodides under the same conditions. Spiro-1,3-indandionolylpyrrolidine derivatives having an array of stereocenters are reported.
Tanım
Dergi veya Seri
SYNTHETIC COMMUNICATIONS
ISSN
0039-7911
ISBN
Haklar
Anahtar Kelimeler
Antidepressant drugs , C-C coupling , isoindoles , spiro-1,3-indandionolylpyrrolidines , tandospirone , DOMINO-HECK REACTIONS , BRIDGED PERHYDROISOINDOLE DERIVATIVES , POTENTIAL PHARMACOLOGICAL AGENTS , SUBSTITUTED TRICYCLIC IMIDES , EXPECTED ANXIOLYTIC ACTIVITY , UNSATURATED DICARBOXIMIDES , ISOXAZOLINE DERIVATIVES , EPIBATIDINE , EPIBOXIDINE , HYDROARYLATIONS , Chemistry