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SYNTHESIS OF NEW TANDOSPIRONE ANALOGUES CARRYING 1-(3-(TRIFLUOROMETHYL)PHENYL)PIPERAZINE

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dc.contributor.authorGunkara, Omer Tahir
dc.contributor.authorSucu, Bilgesu Onur
dc.contributor.authorGuleli, Muge
dc.contributor.authorOcal, Nuket
dc.contributor.institutionauthorGÜNKARA, Ömer Tahir
dc.date.accessioned2026-06-27T13:27:58Z
dc.date.issued2014
dc.description.abstractNew tandospirone analogues containing a 1-[3-(trifluoromethyl) phenyl] piperazine (TFMPP) moiety have been synthesized by hydroarylation reactions with Pd(OAc)(2). The perhydroisoindole derivatives were obtained by the reaction of reduced starting material with aryl-(heteroaryl) iodides under the same conditions. Spiro-1,3-indandionolylpyrrolidine derivatives having an array of stereocenters are reported.en
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [109T380]
dc.description.sponsorshipYildiz Technical University Scientific Research Projects Coordination Department [2011-01-02-KAP03]
dc.description.urihttps://doi.org/10.1080/00397911.2013.865236
dc.identifier.doi10.1080/00397911.2013.865236
dc.identifier.eissn1532-2432
dc.identifier.endpage1628
dc.identifier.issn0039-7911
dc.identifier.issue11
dc.identifier.startpage1619
dc.identifier.urihttps://hdl.handle.net/20.500.14981/52895
dc.identifier.volume44
dc.identifier.wos000337581200006
dc.language.isoeng
dc.publisherTAYLOR & FRANCIS INC
dc.relation.ispartofSYNTHETIC COMMUNICATIONS
dc.rightsopenAccess
dc.subjectAntidepressant drugs
dc.subjectC-C coupling
dc.subjectisoindoles
dc.subjectspiro-1,3-indandionolylpyrrolidines
dc.subjecttandospirone
dc.subjectDOMINO-HECK REACTIONS
dc.subjectBRIDGED PERHYDROISOINDOLE DERIVATIVES
dc.subjectPOTENTIAL PHARMACOLOGICAL AGENTS
dc.subjectSUBSTITUTED TRICYCLIC IMIDES
dc.subjectEXPECTED ANXIOLYTIC ACTIVITY
dc.subjectUNSATURATED DICARBOXIMIDES
dc.subjectISOXAZOLINE DERIVATIVES
dc.subjectEPIBATIDINE
dc.subjectEPIBOXIDINE
dc.subjectHYDROARYLATIONS
dc.subjectChemistry
dc.titleSYNTHESIS OF NEW TANDOSPIRONE ANALOGUES CARRYING 1-(3-(TRIFLUOROMETHYL)PHENYL)PIPERAZINE
dc.typeArticle
dspace.entity.typePublication
local.import.sourceWOS

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